Glaucoma
Glaucoma is the term applied to a group of eye diseases that gradually result in loss of vision by permanently damaging the optic nerve, the nerve that transmits visual images to the brain. The leading cause of irreversible blindness, glaucoma often produces no symptoms until it is too late and vision loss has begun.
Treatments and drugs
The damage caused by glaucoma can't be reversed. But treatment and regular checkups can help slow or prevent vision loss, especially in you catch the disease in its early stage.
The goal of glaucoma treatment is to lower pressure in your eye (intraocular pressure). Depending on your situation, your options may include eye drops, laser treatment or surgery.
Eye drops
Glaucoma treatment often starts with prescription eye drops. These can help decrease eye pressure by improving fluid drains from your eye or by decreasing secretion the amount of fluid .
Prescription eye drop medications include:
Prostaglandins. These increase the outflow of the fluid in your eye (aqueous humor) and reduce pressure in your eye. Examples include latanoprost (Xalatan) and bimatoprost (Lumigan). Possible side effects include mild reddening and stinging of the eyes, darkening of the iris, changes in the pigment of the eyelashes or eyelid skin, and blurred vision.
Beta blockers. These reduce the production of fluid in your eye, thereby lowering the pressure in your eye (intraocular pressure). Examples include timolol (Betimol, Timoptic) and betaxolol (Betoptic). Possible side effects include difficulty breathing, slowed heart rate, lower blood pressure, impotence and fatigue.
Alpha-adrenergic agonists. These reduce the production of aqueous humor and increase outflow of the fluid in your eye. Examples include apraclonidine (Iopidine) and brimonidine (Alphagan). Possible side effects include an irregular heart rate; high blood pressure; fatigue; red, itchy or swollen eyes; and dry mouth.
Carbonic anhydrase inhibitors. Rarely used for glaucoma, these drugs may reduce the production of fluid in your eye. Examples include dorzolamide (Trusopt) and brinzolamide (Azopt). Possible side effects include a metallic taste, frequent urination, and tingling in the fingers and toes.
Miotic or cholinergic agents. These increase the outflow of fluid from your eye. An example is pilo carpine (Isopto Carpine). Side effects include smaller pupils, possible blurred or dim vision, and nearsightedness.
Oral medications
If eye drops alone don't bring your eye pressure down to the desired level, your doctor may also prescribe an oral medication, usually a carbonic anhydrase inhibitor. Possible side effects include frequent urination, tingling in the fingers and toes, depression, stomach upset, and kidney stones.
Surgery and other therapies
Other treatment options include laser therapy and various surgical procedures. Possible complications include pain, redness, infection, inflammation, bleeding, abnormally high or low eye pressure, and loss of vision. Some types of eye surgery may speed the development of cataracts.
You'll need to see your doctor for follow-up exams. And you may eventually need to undergo additional procedures if your eye pressure begins to rise or other changes occur in your eye.
The following techniques are intended to improve the drainage of fluid within the eye, lowering pressure:
Laser therapy. Laser trabeculoplasty is an option for people with open-angle glaucoma. It's done in your doctor's office. He or she uses a laser beam to open clogged channels in the trabecular meshwork. It may take a few weeks before the full effect of this procedure becomes apparent.
Filtering surgery. With a surgical procedure called a trabeculectomy, your surgeon creates an opening in the white of the eye (sclera) and removes part of the trabecular meshwork.
Drainage tubes. In this procedure, your eye surgeon inserts a small tube in your eye.
Electrocautery. Your doctor may suggest a minimally invasive procedure to remove tissue from the trabecular meshwork using a small electrocautery device called a Trabecutome.
Glaucoma surgery advantages:
Reduced Intraocular Pressure (IOP): Surgery aims to lower IOP, which is crucial in preventing optic nerve damage.
Improved Vision Preservation: By effectively managing pressure, surgery can help preserve existing vision and prevent further loss.
Long-term Control: Surgical options can provide more lasting pressure control compared to medications, reducing the need for daily eye drops.
Fewer Side Effects: Some patients may experience fewer side effects compared to long-term medication use.
Customization: Various surgical techniques can be tailored to individual patient needs, whether it’s trabeculectomy, tube shunt surgery, or minimally invasive procedures.
Increased Quality of Life: By reducing the burden of daily medication and improving eye health, patients may experience an overall enhancement in their quality of life.
Discussing options with an eye care specialist can help determine the best approach for individual circumstances.
Treating acute angle-closure glaucoma
Acute angle-closure glaucoma is a medical emergency. If you're diagnosed with this condition, you'll need urgent treatment to reduce the pressure in your eye. This generally will require both medication and laser or other surgical procedures.
You may have a procedure called a laser peripheral iridotomy in which the doctor creates a small hole in your iris using a laser. This allows fluid (aqueous humor) to flow through it, relieving eye pressure.
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